Regulation of Pathways

Readings

Module 8

Garrett and Grisham

• Chapter 10
  • section 8 general considerations
  • section 9 Allosteric regulation of enzyme activity
  • section 10 A model for allosteric behaviour
  • section 11 glycogen phosphorylase
• Chapter 12
  • section 5 - hemoglobin
• Chapter 15
  • section 3 - page 478 regulation of phosphofructokinase
• Chapter 16
  • section 3 - page 501 structure and regulation of citrate synthase
  • sections 14 regulation of the TCA cycle
• Chapter 17
  • section 8 - thermodynamic view of chemiosmotic coupling
    note: we supposede;ly read this last module... but it does contain the theory of regulation in electron transport system (all thermodynamics)
• Chapter 19
  • section 5 - control of glucogen synthesis

Problems

• required and graded
  • short answer questions (see page 3 of this module)
  • multiple choice quiz (see page 4 of this module)
• The following problems from the text book do not need to be handed in, however, you may find them helpful.
  • chapter 10
    • problems 7, 8, 11, 12