Hill Coeffcient Tutorial
We will return to this kinetics simulator one final time
- Move the Km slider to it minimum number
- Move the [S] slider out to about 2 or so
- Make note of the rate that results (look at the digital readout in the middle panel)
- Now move the "Hill coefficient" slider up toward 3
- Make note of what happens to the red line in the graph as you slide it
- Make note of how much the rate decreases at this [S].
The rate can be controlled in excess of FOUR Orders of Magnitude. We did NOT change anything but the Hill coefficient.